谢院生，男，解放军总医院（301医院）肾内科主任医师、教授，医学博士，研究生导师。现任国家重点学科、中国人民解放军总医院全军肾脏病研究所副所长，中国中西医结合学会肾病专业委员会常委、北京中西医结合学会肾病专业委员会副主任委员、《中国中西医结合肾病杂志》编委，国家自然科学基金同行评议专家，《中华医学杂志》、《中华肾脏病杂志》、《中华高血压杂志》等特邀审稿专家。留学日本5年，在日本获医学博士学位。长期从事肾内科的临床工作，具有丰富的临床经验。主要研究方向为中西医结合诊治IgA肾病、糖尿病肾病、高血压等，在IgA 肾病、肾脏损伤的机制和促进修复再生的干预措施以及肾脏病理方面有很高的学术造诣。在国内外医学刊物署名发表论文全文60篇，其中SCI论文全文19篇，累计影响因子85。 第一作者论文已被SCI（包括Nature Medicine等著名杂志和国际最著名的肾脏病学著作The Kidney）引用130余次。合作出版肾脏病学著作1部。在国际学术会议发表论著摘要39篇，在国内学术会议作学术讲座15次。作为课题负责人承担国家自然科学基金课题和北京市课题各1项，作为国家自然科学基金创新研究群体的主要学术骨干参与1项国家自然科学基金重点项目和2项国家重点基础发展计划“973”项目。2002年获第26届国际内科学会青年学者奖。作为主要完成人，获2006年国家科技进步二等奖、2005年北京市科学技术一等奖、2005年中华医学科技一等奖各1项。
署名发表SCI论文全文19篇

1.Xie Y, Nishi S, Iguchi S, Imai N, Sakatsume M, Saito A, Ikegame M, Iino N, Shimada H, Ueno M, Kawashima H, Arakawa M, and Gejyo F. Expression of osteopontin in gentamicin-induced acute tubular necrosis and its recovery process. Kidney Int. 2001; 59(3): 959-74.

2.Xie Y, Sakatsume M, Nishi S, Narita I, Arakawa M, and Gejyo F. Expression, roles, receptors, and regulation of osteopontin in the kidney. Kidney Int. 2001; 60(5): 1645-57.

3.Sakatsume M, Xie Y, Ueno M, Obayashi H, Goto S, Narita I, Homma N, Tasaki K，Suzuki Y, and Gejyo F. Human glomerulonephritis accompanied by active cellular infiltrates shows effector T cells in urine. J Am Soc Nephrol. 2001; 12(12): 2636-44.

4.Kaneko Y, Sakatsume M, Xie Y, Kuroda T, Igashima M, Narita I, Gejyo F. Macrophage metalloelastase as a major factor for glomerular injury in anti-glomerular basement membrane nephritis. J Immunol. 2003; 170(6): 3377-85.

5.Xie Y, Nishi S, Ueno M, Imai N, Sakatsume M, Narita I, Suzuki Y, Akazawa K, Shimada H, Arakawa M, Gejyo F. The efficacy of tonsillectomy on long-term renal survival in patients with IgA nephropathy. Kidney Int. 2003; 63(5): 1861-7.

6.Xie Y, Nishi S, Fukase S, Nakamura H, Chen X, Imai N, Sakatsume M, Saito A,
Ueno M, Narita I, Yamamoto T, and Gejyo F. Different type and localization of CD44 on surface membrane of regenerative renal tubular epithelial cells in vivo. Am J Nephrol. 2004; 24(2): 188-97.

7.Xie Y, Chen X, Nishi S, Narita I, Gejyo F. Relationship between tonsils and IgA nephropathy as well as indications of tonsillectomy. Kidney Int 2004; 65(4): 1135-44.

8.Chen X, Qiu Q, Tang L, Liu S, Cai G, Liu H, Xie Y. Effects of co-administration of urokinase and benazepril on severe IgA nephropathy. Nephrol Dial Transplant. 2004;19(4): 852-7.

9.Hama H, Saito A, Takeda T, Tanuma A, Xie Y, Sato K, Kazama JJ, Gejyo F. Evidence indicating that renal tubular metabolism of leptin is mediated by megalin but not by the leptin receptors. Endocrinology. 2004;145(8): 3935-40.

10.Li Z, Chen X, Xie Y, Shi S, Feng Z, Fu B, Zhang X, Cai G, Wu C, Wu D, Gu Y. Expression and significance of integrin-linked kinase in cultured cells, normal tissue, and diseased tissue of aging rat kidneys. J Gerontol A Biol Sci Med Sci. 2004; 59(10): 984-96.

11.Nishi S, Xie Y, Ueno M, Imai N, Suzuki Y, Iguchi S, Fukase S, Mori H, Alchi B, Shimada H, Arakawa M, Gejyo F. A clinicopathological study on the long-term efficacy of tonsillectomy in patients with IgA nephropathy. Acta Otolaryngol. 2004; (555): 49-53.

12.Wu J, Chen X, Xie Y, Yamanaka N, Shi S, Wu D, Liu S, and Cai G. Characteristics and risk factors of intrarenal arterial lesions in patients with IgA nephropathy. Nephrol Dial Transplant. 2005; 20(4): 719-27.

13.Qiao X, Chen X, Wu D, Ding R, Wang J, Hong Q, Shi S, Li J, Xie Y, Lu Y, Wang Z. Mitochondrial pathway is responsible for aging-related increase of tubular cell apoptosis in renal ischemia/reperfusion injury. J Gerontol A Biol Sci Med Sci. 2005; 60(7): 830-9.

14.Yan QJ, Chen XM, Zhang YM, Xie Y, Shi SZ, Fu B, Hong Q, Xu GS, Zhang XG, Zhu HY, Wu D, Lu Y, Zhang YH. NANOG changes in mouse kidneys with age. Rejuvenation Res. 2005; 8(4): 248-53.

15.Zhang X, Chen X, Hong Q, Lin H, Zhu H, Liu Q, Wang J, Xie Y, Shang X, Shi S, Lu Y, Yin Z. TIMP-1 promoted age-related renal fibrosis through upregulating ICAM-1 in human TIMP-1 transgenic mice. J Gerontol A Biol Sci Med Sci. 2006；61（11）：1130-1143.

16.Jiang H, Zhu H, Chen X, Peng Y, Wang J, Liu F, Shi S, Fu B, Lu Y, Hong Q, Feng Z, Hou K, Sun X, Cai G, Zhang X, Xie Y. TIMP-1 Transgenic Mice Recover From Diabetes Induced by Multiple Low-Dose Streptozotocin. Diabetes. 2007; 56(1): 49-56.

17.Xie Y, Chen X. Epidemiology, major outcomes, risk factors, prevention and management of chronic kidney disease in China. Am J Nephrol. 2008; 28(1):1-7

18.Tu X, Chen X, Xie Y, Shi S, Wang J, Chen Y, Li J. Anti-inflammatory renoprotective effect of the combination therapy of clopidogrel with irbesartan on 5/6 nephrectomized rats. J Am Soc Nephrol. 2008; in press

19.Zhou J, Chen X, Xie Y, Li J, Yamanaka N, Tong X. A Differential Diagnostic Model of Diabetic Nephropathy and Non-Diabetic Renal Diseases. Nephrol Dial Transplant. 2008; in press